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In the study, researchers classified participants according to their body mass index (BMI), which is a measure of total body fat and is calculated by dividing a person’s weight in kilograms by their height in meters squared. BMI classifications (kilogram/meter-squared) are:
Normal weight: 18.5-24.9
Overweight: 25.0- 29.9
Class I obesity: 30.0-34.9
Class II obesity: 35.0-39.9
Class III obesity: 40.0 or higher
The researchers found that the risk of dying overall and from most major health causes rose continuously with increasing BMI within the class III obesity group. Statistical analyses of the pooled data indicated that the excess numbers of deaths in the class III obesity group were mostly due to heart disease, cancer and diabetes. Years of life lost ranged from 6.5 years for participants with a BMI of 40-44.9 to 13.7 years for a BMI of 55-59.9. To provide context, the researchers found that the number of years of life lost for class III obesity was equal or higher than that of current (versus never) cigarette smokers among normal-weight participants in the same study.
The accuracy of the study findings is limited by the use of mostly self-reported height and weight measurements and by the use of BMI as the sole measure of obesity. Nevertheless, the researchers noted, the results highlight the need to develop more effective interventions to combat the growing public health problem of extreme obesity.
“Given our findings, it appears that class III obesity is increasing and may soon emerge as a major cause of early death in this and other countries worldwide,” said Patricia Hartge, Sc.D., Division of Cancer Epidemiology and Genetics, and senior author of the study.
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Being overweight or obese isn't a cosmetic problem. These conditions greatly raise your risk for other health problems.
Overweight and Obesity-Related Health Problems in Adults
1.Coronary Heart Disease
As your body mass index rises, so does your risk for coronary heart disease (CHD). CHD is a condition in which a waxy substance called plaque (plak) builds up inside the coronary arteries. These arteries supply oxygen-rich blood to your heart. Plaque can narrow or block the coronary arteries and reduce blood flow to the heart muscle. This can cause angina (an-JI-nun or AN-jug-nun) or a heart attack. (Angina is chest pain or discomfort.)Obesity also can lead to heart failure. This is a serious condition in which your heart can't pump enough blood to meet your body's needs.
2.High Blood Pressure
Blood pressure is the force of blood pushing against the walls of the arteries as the heart pumps blood. If this pressure rises and stays high over time, it can damage the body in many ways. Your chances of having high blood pressure are greater if you're overweight or obese.
3.Stroke
Being overweight or obese can lead to a buildup of plaque in your arteries. Eventually, an area of plaque can rupture, causing a blood clot to form. If the clot is close to your brain, it can block the flow of blood and oxygen to your brain and cause a stroke. The risk of having a stroke rises as BMI increases.
4.Type 2 Diabetes
Diabetes is a disease in which the body's blood glucose, or blood sugar, level is too high. Normally, the body breaks down food into glucose and then carries it to cells throughout the body. The cells use a hormone called insulin to turn the glucose into energy. In type 2 diabetes, the body's cells don't use insulin properly. At first, the body reacts by making more insulin. Over time, however, the body can't make enough insulin to control its blood sugar level. Diabetes is a leading cause of early death, CHD, stroke, kidney disease, and blindness. Most people who have type 2 diabetes are overweight.
5.Abnormal Blood Fats
If you're overweight or obese, you're at increased risk of having abnormal levels of blood fats. These include high levels of triglycerides and LDL ("bad") cholesterol and low levels of HDL ("good") cholesterol. Abnormal levels of these blood fats are a risk factor for CHD. For more information about triglycerides and LDL and HDL cholesterol, go to the Health Topics Cholesterol article.
6.Metabolic Syndrome
Metabolic syndrome is the name for a group of risk factors that raises your risk for heart disease and other health problems, such as diabetes and stroke. You can develop any one of these risk factors by itself, but they tend to occur together. A diagnosis of metabolic syndrome is made if you have at least three of the following risk factors:
· A large waistline. This is called abdominal obesity or "having an apple shape." Having extra fat in the waist area is a greater risk factor for CHD than having extra fat in other parts of the body, such as on the hips.
· A higher than normal triglyceride level (or you're on medicine to treat high triglycerides).
· A lower than normal HDL cholesterol level (or you're on medicine to treat low HDL cholesterol).
· Higher than normal blood pressure (or you're on medicine to treat high blood pressure).
· Higher than normal fasting blood sugar (or you're on medicine to treat diabetes).
7. Cancer
Being overweight or obese raises your risk for colon, breast, endometrial, and gallbladder cancers.
8. Osteoarthritis
Osteoarthritis is a common joint problem of the knees, hips, and lower back. The condition occurs if the tissue that protects the joints wears away. Extra weight can put more pressure and wear on joints, causing pain.
9.Sleep Apnea
Sleep apnea is a common disorder in which you have one or more pauses in breathing or shallow breaths while you sleep. A person who has sleep apnea may have more fat stored around the neck. This can narrow the airway, making it hard to breathe.
10.Obesity Hypoventilation Syndrome
Obesity hypoventilation syndrome (OHS) is a breathing disorder that affects some obese people. In OHS, poor breathing results in too much carbon dioxide (hypoventilation) and too little oxygen in the blood (hypoxemia).OHS can lead to serious health problems and may even cause death.
11.Reproductive Problems
Obesity can cause menstrual issues and infertility in women.
12.Gallstones
Gallstones are hard pieces of stone-like material that form in the gallbladder. They're mostly made of cholesterol. Gallstones can cause stomach or back pain. People who are overweight or obese are at increased risk of having gallstones. Also, being overweight may result in an enlarged gallbladder that doesn't work well.
13. Your Skin
It’s easy to forget how much obesity can damage the skin, and contrary to popular opinion, cosmetic blemishes like stretch marks aren’t the only consequence. Hormone changes can cause acanthosis nigricans, a thickening and darkening of the skin; swelling and stretching of the skin can cause redness and irritation, known as stasis dermatitis; and poor vein function can lead to ulcers, found most often in ankles as a result of lacking blood flow.
Maintaining healthy skin is also more than a cosmetic concern. The outer layers of your skin are the foremost barrier to your bloodstream, which means they also serve as the gatekeeper for infectious agents. What begins as a stretched layer of skin may turn into serious illness, all because the body’s mass outmatched the skin’s elasticity.
14. Your Lungs
Like the arteries surrounding your heart, your lungs face great risk in the presence of excess fat. A study published in 2010 showed large amounts of adipose tissue diminishes the organs’ overall capacity for air. This in itself poses significant risk for poor ventilation, which can both exacerbate existing respiratory diseases or produce the same side effects even in the absence of those diseases.
Poor lung function means blood vessels may not be getting enough oxygen. Similarly, obese people face a far greater risk for obstructive sleep apnea than non-obese people, further limiting the oxygen their bodies take in. Problematic enough during the daytime, a failure to breathe at night could turn fatal in a hurry. Researchers are working on a device that delivers tiny electric pulses into the tongue, to release the blockage without waking people up.
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Overweight and obesity affect Americans and Africans of all ages, sexes, and racial/ethnic groups. This serious health problem has been gro...